Prof. Dr. Zeki YILDIRIM

ÜNVANI: GÖĞÜS HASTALIKLARI UZMANI, PROF. DR. ZEKİ YILDIRIM zeki

DOĞUM TARİHİ VE YERİ: 01. 01. 1965, ÇANKIRI

TIP EĞİTİMİ :

Uludağ Üniversitesi Tıp Fakültesi, Bursa
MEZUNİYET SONRASI EĞİTİMİ:

Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Merkezi, Ankara
University of Teaxas, MD Anderson Cancer Center, Thoracic Medical Oncology, Houston. Texas, USA (Postdoctoral Research Fellow)
ÇALIŞMA YER VE SÜRELERİ:

Gençlik ve spor Genel Müdürlüğü, Ankara
Pratisyen Hekim Ankara (Zorunlu Hizmet) 1989-1991
Atatürk göğüs Hastalıkları ve göğüs Cerrahisi Merkezi Ankara Uzmanlık Eğitimi 1991-1995
İnönü Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı Öğretim Üyesi Malatya (Yrd.Doçent) 1886-1999, DOÇENT 1999 – 2005
Atatürk göğüs Hastalıkları ve göğüs Cerrahisi Merkezi Ankara (Klinik Şefi) 2005
Fatih Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı Ankara (Prof) 2005-2013
Gazi Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı 2013-2016
Özel Kudret International Hospital Göğüs Hastalıkları Anabilim Dalı 2017
İDARİ GÖREVLER:

İnönü Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı Başkanlığı

Fatih Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı Başkanlığı

MESLEKİ DERNEK ÜYELİKLERİ:

AMERİCAN THORACİC SOCİETY
European Respiratory Society

TORAKS DERNEĞİ

HAKEMLİK YAPTIĞI DERGİLER :

CLİNİCA CHİMİCAACTA
Pharmacological Research

Tuberküloz ve Toraks Dergisi

Van Tıp Dergisi

Ankara Hastanesi Dergisi

Dicle Tıp Dergisi

Tıp Araştırmaları Dergisi

Turkish Journal of Medical Science

ALDIĞI ÖDÜLLER :

TORAKS DERNEĞİ 2005 YILI YURT DIŞI YAYIN ÖDÜLÜ (BİRİNCİLİK)
TORAKS DERNEĞİ 2003 YILI YURT DIŞI YAYIN ÖDÜLÜ (ÜÇÜNCÜLÜK)
Toraks Derneği 2000 yılı sözel sunum birincilik ödülü

Türkiye Solunum Araştırmaları Derneği 1999 yılı kongresi poster sunumu 10.luk ödülü

YAYINLAR :

Makaleler
Yildirim Z, Turkkani MH, Bozkurt H, Islek E, Mollahaliloglu S, Erkoc Y. Effects of the Health Transformation Programme on tuberculosis burden in Turkey. Respir Med. Respir Med. 2013;107:2029-37.
Turkay C, Ozol D, Kasapoglu B, Kirbas I, Yildirim Z, Yigitoglu R. Influence of Obstructive Sleep Apnea on Fatty Liver Disease: Role of Chronic Intermittent Hypoxia. Respir Care 2012;57:244-9.
Yildirim, Z; Sogut, Sadik; Koksal, Nurhan; et al.I ncreased nitrite levels in exhaled breath condensate in asthma-like syndrome induced by occupational sulfur dioxide exposure. Turk J Med Sci 2012; 42: 425-431
Akgedik R, Akgedik S, Karamanlı H, Uysal S, Bozkurt B, Ozol D, Armutcu F, Yıldırım Z. Effect of resveratrol on treatment of bleomycin-induced pulmonary fibrosis in rats. 2012;35:1732-41.
Ozol D, Turkay C, Kasapoglu B, Karamanlı H, Yıldırım Z. Relationship between components of metabolic syndrome and polysomnographic findings in obstructive sleep apnea.Metab Syndr Relat Disord. 2011;9:13-8.
Ayrım A, Keskin EA, Ozol D, Onaran Y, Yıldırım Z, Kafali H. Influence of self-reported snoring and witnessed sleep apnea on gestational hypertension and fetal outcome in pregnancy. Arch Gynecol Obstet 2011; 283: 195-199
Ozol D, Carlıoğlu A, Karamanlı H, Akgedik R, Karakurt F, Yıldırım Z. Influence of snoring on microalbuminuria in diabetic patients.Sleep Breath2011;15:295-300
Ermis H, Gokirmak M, Yildirim Z, Yologlu S, Ankarali H. Exposure to SO2 does not have a chronic effect on pulmonary functions of apricot workers. Inhalation Toxicology 2010; 22: 219-223.
Yildirim Z, Bozkurt B, Ozol D, Armutcu F, Akgedik R, Karamanli H, Kizilirmak D, İkizek M. Increased Exhaled 8-Isoprostane and Interleukin-6 in Patients with Helicobacter pylori infection. Helicobacter 2016;21:389-94.
Ateş H, Ateş İ, Bozkurt B, Çelik HT, Özol D, Yildirim Z. What is the most reliable marker in the differential diagnosis of pulmonary embolism and community-acquired pneumonia? Blood Coagul Fibrinolysis. 2016;27:252-8.
Özol D, Karamanli H, Uysal S, Yığıtoğlu MR, Yildirim Z. Airway inflammation and tiotropium treatment in stable COPD patients. Turk J Med Sci. 2014;44:804-8.
Karamanlı H, Ozol D, Ugur KS, Yıldırım Z, Armutçu F, Bozkurt B, Yigitoglu R. Influence of CPAP treatment on airway and systemic inflammation in OSAS patients. Sleep Breath. 2014; 18;251-56.
Aydin M, Koca C, Ozol D, Uysal S, Yildirim Z, Kavakli HS, Yigitoglu MR Interaction of metabolic syndrome with asthma in postmenopausal women: role of adipokines. Inflammation. 2013;36:1232-8.

Kurtaran H, Ark N, Sadikoglu F, Ugur KS, Yildirim Z, Aktas D. The effect of anterior nasal packing with airway tubes on pulmonary function following septoplasty. Turk J Med Sci 2009; 39: 537-540.

Corut A, Senyigit A, Ugur SA, Altin S, Ozcelik U, Calisir H, Yildirim Z, Gocmen A, Tolun A. Mutations in SLC34A2 Cause Pulmonary Alveolar Microlithiasis and are Possibly Associated with Testicular Microlithiasis. Am J Hum Genet. 2006; 79: 650-6.

Ozol D, Uz E, Bozalan R, Türkay C, Yildirim Z. Relationship between asthma and irritable bowel syndrome: role of food allergy. J Asthma.2006 ;43:773-5.

Iraz M, Erdogan H, Kotuk M, Yagmurca M, Kilic T, Ermis H, Fadillioglu E, Yildirim Z. Ginkgo biloba inhibits bleomycin-induced lung fibrosis in rats.Pharmacol Res. 2006; 53: 310-316.
Erdogan H, Fadillioglu E, Kotuk M, Iraz M, Tasdemir Y, Oztas Y, Yildirim Z. Effects of Ginkgo biloba on plasma oxidant injury induced by bleomycin in rats.Toxicology and Industrial Helath 2006; 22: 47-52.

Hasanoglu HC, Yildirim Z, Ermis H, Kilic T, Koksal N. Lung cancer and mesothelioma in towns with environmental exposure to asbestos in eastern Anatolia. Int Arch of Occupational and Environ Med 2006; 79: 89-91.

Ozerol IH, Bayraktar M, Çizmeci Z, Durmaz R, Akbas E, Yildirim Z, Yologlu S. Legionnaires’ disease: a nosocomial outbreak in Turkey. J Hospital Infection 2006; 62:50-7.
Yildirim Z, Kotuk M, ErdoganH, Iraz M, YagmurcaM, Kuku I, FadilliogluE. preventive effect of melatonin on bleomycin-induced lung fibrosis in rats. Journal of Pineal Research 2006; 40:27-33

Yildirim Z, Kotuk M, Iraz M, Kuku I, Ulu R, Armutcu F, Ozen S. Attenuation of bleomycin-induced lung fibrosis by oral sulfhydryl containing antioxidants in rats: Erdosteine and N-acetylcysteine. Pulmonary Pharmacology and Therapeutic 2005;18:367-373.

Yildirim Z, Kilic T, Koksal N, Kotuk M. Protective effect of ipratropium bromide on bronchoconstriction induced by sulfur dioxide exposure during apricot sulfurization processes that causes asthma-like syndrome in agricultural environment. Phamacological Research 2005; 51: 479-482.

Taskapan H, Ulu R, Gulu H, Taskapan MC, Yildirim Z, Kosar F, Sahin I, Kaya M. Interdialitic weight gain and pulmonary membran diffusing capacity in patints on hemodialysis. International Urology and Nephrology. 2004;36: 583-586.

Yildirim Z, Turkoz Y, Kotuk M, Armutcu F, Gurel A, Iraz M, Ozen S, Aydogdu I, Akyol O. Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats. Nitric Oxide 2004; 11: 156-165.

Hepsen I, Yildirim Z, Yilmaz H, Kotuk M. The preventive effect of lacrimal occlusion on topical timolol-induced bronchoconstriction in asthmatics. Clinical and Experimental Ophtalmology 2004; 32: 597-602.

Sogut S, Ozyurt H, Armutcu F, Kart L, Iraz M, Akyol O, Ozen S, Kaplan S, Temel I, Yildirim Z. Erdosteine prevents bleomycin-induced pulmonary fibrosis in rats. European Journal of Pharmacology 2004;494: 213-220.

OzyurtH, Sogut,S, Yildirim Z, KartL, Iraz M, ArmutçuF,TemelI, OzenS, UzunA, Akyol O. Inhibitory effect of caffeic acid phenethyl ester (cape) on bleomycine-induced lung fıbrosis in rats. Clin Chim Acta 2004; 339: 65-75.

Ozyurt H, Yildirim Z, Kotuk M, Yilmaz HR, Yagmurca M, Iraz M, Sogut S, Akyol O. Cisplatin-induced acute renal failure is ameliorated erdosteine in a dose-dependent manner. Journal of Applied Toxicology 2004; 24:269-275.

Yildirim Z, Hacievliyagil S, Kutlu NO, Aydin NE, Kürkçüoğlu M, Iraz M, DurmazR, Effect of water extract of Turkish propolis on tuberculosis infection in guinea pigs. Pharmacological Research 2004; 49: 287-292.

Sogut S, Kotuk M, Yilmaz HR, Ulu R, Ozyurt H, YildirimZ. In vivo evidence suggesting a role for purine catabolizing enzymes in pathogenesis of cisplatin-induced nephrotoxicity in rats and effect of erdosteine against this toxicity. Cell Biochem and Func. 2004; 22:157-162.

Yilmaz HR, Iraz M, Sogut S, Ozyurt H, Yildirim Z, Akyol O. The effects of erdosteine on the activities of some metabolic enzymes during cisplatin-induced nephrotoxicity in rats. Pharmacological Research 2004; 50: 287-290.

Ozen S, Akyol O, Iraz M, Sogut S, Ozugurlu F, Ozyurt H, Odaci E, Yildirim Z. The role of caffeic acid phenethyl ester, an active component of propolis, against cisplatin-induced nephrotoxicity in rats. Journal of Applied Toxicology 2004; 24: 27-35.

Koksal N, Hasanoglu HC, Gokirmak M, Yildirim Z, Gultek A. Apricot sulfurization: an occupation that induces asthma-like syndrome in agricultural environment. Am J Ind Med. 2003; 43: 447-53.
Koksal N, Yildirim Z, Gokirmak M, Hasanoglu HC, Mehmet N, Avci H. The role of nitric oxide and cytokines in asthma-like syndrome induced by sulfur dioxide exposure in agricultural environment. Clin Chim Acta 2003; 336: 115-122.

Gokirmak M, YildirimZ, Hasanoglu HC, Koksal N, MehmetN. The role of oxidative stress in bronchoconstriction due to occupational sulfur dioxide exposure. Clin Chim Acta. 2003; 331: 119-26.

Pekdemir H,Camsari A, Akkus MN, Cicek D, Tuncer C, Yildirim Z. Impaired cardiac autonomic functions in patients with environmental asbestos exposure: a study of time domain heart rate variability. Journal of Electrocardiology 2003; 39: 195-203.

Hasanoglu HC, Gokirmak M, Baysal T, Yildirim Z, Koksal N, Onal Y. Environmental exposure to tremolite and chrysotile asbestos in eastern Turkey. Arch Environ Health 2003; 58: 144-150.

Hasanoglu HC, Yildirim Z, Hasanoglu A, Ozcan C, Gokirmak M, Koksal N, Kalkan S. Effects of ranitidine on pulmonary function tests of patients with chronic obstructive pulmonary disease. Pharmacol Res 2003; 47: 535-539.

Yildirim Z, Sogut S , Odaci E, Iraz M, Ozyurt H, Kotuk M, Akyol O. Oral erdosteine administration attenuates cisplatin-induced renal tubular damage in rats. Pharmacol Res 2003; 47:149-156.

Gökırmak M, Hasanoğlu HC, Köksal N, Yildirim Z, Hacıevliyagil SS, Soysal O. Retrieving aspirated pins by flexible bronchoscopy. Journal of Bronchology 2002; 9: 10-14.
Hasanoglu HC, Gökırmak M, Yıldırım Z, Köksal N, Cokkeser Y. Flexible bronchoscopy: Is atropine necessary for premedication. Journal of Bronchology 2001: 8; 5-9.
Akyol O, Gokbulut I, Koksal N, Akin H, Ozyurt H, Yildirim Z. The activities of purine catabolizing enzymes in plasma and bronchial washing fluid in patients with lung cancer and pneumonia. Clin Biochem 2001; 34: 251-254.
Yilmaz Turay U, Yildirim Z, Turkoz Y, Biber C, Erdogan Y, Keyf AI, Ugurman F, Ayaz A, Ergun P, Harputluoglu Y.Use of pleural fluid C-reactive protein in diagnosis of pleural effusions. Respir Med 2000; 94: 432-5.

Yildirim Z, Hasanoglu HC, Akyol O, Gokirmak M, Koksal N. Serum adenosine deaminase activities in lung cancer and mesothelioma. Clin Biochem 1999; 32: 283-5.

Ucar G, Yildirim Z, Ataol E, Erdogan Y, Biber C. Serum angiotensin converting enzyme activity in pulmonary diseases: correlation with lung function parameters. Life Sci 1997; 61: 1075-82.
B. Olgu Sunumları

Kutlu R, Alkan A, Sigirci A, Altinok T, Yildirim Z. Temporary and Permanent Inferior Vena Cava Filter Combination in a Young Patient: To Implant or Not to Implant? Cardiovasc Intervent Radiol. 2003; 26: 492-495.
Sevinc A, Hasanoglu HC, Gokirmak M, Yildirim Z, Baysal T, Mizrak B. Allergic granulomatosis and angitis in the absence of asthma and eosinohilia: A rare presentation of Churge-Strauss syndrome. Rheumatol Int. 2004; 24: 301-304.
Yildirim Z, Soysal O, Gökırmak M, Berat H, Mızrak B, Hasanoğlu HC. Endoronchial inflammatory pseudotumor: A cause of chronic cough. Asian Cardiovasc Thoracic Ann 1999; 7: 326-28.
Atasoy C, Kaya A, Fitoz S, Yildirim Z. Discrete pleural nodules associated with a parasternal mass: an unusual manifestation of tuberculosis. J Thorac Imaging 2002; 17: 74-7.
Hasanoglu HC, Yildirim Z, Gokirmak M. Tumor markers in sputum of patients with bronchioloalveolar carcinoma. Chest 1998; 113: 1144.

Kongre Aktiviteleri

C.1. Bildiri sunarak katıldığı kongreler

Kızırmak D, Karamanlı H, Ozol D, Yiğitioğlu R, Yıldırım Z. Does obesitiy effect inflammatory factors in patient with OSAS? Sleep and Breatihing. Second International Conferences. 11-13 Apiril 2013. Berlin Germany.
Yildirim Z, Turkkani MH, Bozkurt H, Islek E, Mollahaliloglu S, Erkoc Y. Effects of the Health Transformation Programme on tuberculosis burden in Turkey. (poster) American Thoracic Society 2013 International Conference, May 17-22, 2013 – Philadelphia Pennsylvania.
Ozol D, Carlioglu A, Karamanli H, Akgedik R, Yildirim Z. Relationship Between Snoring-Sleep Apne and Diabetic Complications. 20th ERS annual Congress, Barcelona, Spain. September 18-22 2010. Eur Respir J 2010; E2248
Yıldırım Z, Yılmaz H, Hepsen İF. Collagen punctal plug may prevents bronchoconstriction caused by timolol maleat administration to the eye in asthmatic patients. 2003 International Conference May 16-21 Seattle Washington American Thoracic Society. Am J Respir Crit Care Med 2003; 176 (suppl 7): A637.

Yılmaz HR, Söğüt S, Özyurt H, Iraz M, Yıldırım Z, Akyol Ö. The effect of erdosteine and caffeic acid phenethyl ester on the activities of some metabolic enzymes after cisplatin-induced nephrotoxicity in rats. 12th European Respiratory Society Annual Congress, Stocholm 2002. Eur Respir J; 2002; Sppl 38: 71S.

Yıldırım Z, Söğüt S, Iraz M, Özyurt H, Kotuk M, Akyol O. Protective effect of oral erdosteine administration on cisplatin-induced nephrotoxicity in rats. 12th European Respiratory Society Annual Congress, Stocholm 2002. Eur Respir J; 2002; Sppl 38: 74S.

Gökırmak M, Köksal N, Orhan Z, Hacıevliyagil S, Yıldırım Z, Hasanoğlu HC. Effect of environmentatal asbest oxposure on pulmonary functions and arterial blood gases. 12th European Respiratory Society Annual Congress, Stocholm 2002. Eur Respir J; 2002; Sppl 38: 126S.

Hüseyin Özyurt, Söğüt S, Akyol Ö, Kart L, Iraz M, Yıldırım Z, Armutcu F, Temel İ. İnhibtor effect of caffeic acid phenethyl ester on bleomycine-induced lung fibrosis in rats. 12th European Respiratory Society Annual Congress, Stocholm 2002. Eur Respir J; 2002; Sppl 38: 487S.

Söğüt S, Özyurt H, Akyol Ö, Kart L, Iraz M, Yıldırım Z, Armutcu F, Temel İ. Protection of erdosteine on bleomycine-induced lung fibrosis in rats. 12th European Respiratory Society Annual Congress, Stocholm 2002. Eur Respir J; 2002; Sppl 38: 487S.

Yıldırım Z, Hacıevliyagil SS, Kutlu NO, Aydın NE, Iraz M. Effect of propolis on tuberculosis infection in guinea pigs. 12th European Respiratory Society Annual Congress, Stocholm 2002. Eur Respir J; 2002; Sppl 38: 558S.

Söğüt S, Kotuk M, Yıldırım Z. Erdosteine attenutes cisplatin-induced nephrotoxicity by affecting the activities of glutathione preoxidase, xanthine oxidase and adenosine deaminase in the damaged renal tissue in rats. 8th Central european lung cancer conferences, Vienna 2002. Lung Cancer 2002; 37(suppl 1): 36S.

Gökırmak M, Hasanoğlu HC, Yıldırım Z, Köksal N, Orhan Z, Hacıevliyagil SS.The success rates in community-acquired pneumonia treated consistently or inconsistently with the Turkish Thoracic Society pneumonia guidelines. European Respiratory Society Annual Congress, Berlin 2001.

Hasanoğlu HC, Gökırmak M, Köksal N, Baysal T, Yıldırım Z, Hacıevliyagil SS. A high incidence of asbestos related disorders due to environmental asbestos in a town in eastern Turkey. European Respiratory Society Annual Congress, Berlin 2001.

Gokbulut İ, Ozyurt H, Koksal N, Haluk A, Yildirim Z, Akyol O. The activities of purine catabolizing enzymes in plasma and bronchial washing fluid in patients with lung cancer and pneumonia. Balcan Journal of Clinical Laboratory 2001; 8; 54.

Gökırmak M, Hasanoğlu HC, Köksal N, Mehmet N, Yıldırım Z, Çığlı A. Occupational exposure to sulfur dioxide increases serum TNF-a, IL-1b, IL-6, IL-8, nitrite and nitrate levels. World Congess on Lung Health and 10th ERS Annual Congress, Florence 2000. Eur Respir J 2000; 16 Suppl 31: 230S.

Gökırmak M, Hasanoğlu HC, Köksal N, Orhan Z, Hacıevliyagil S, Yıldırım Z. The value of measuring CEA, CA 125, CA 15-3 and CA 19-9 in serum and bronchial washing fluids as a diagnostic aid in lung cancer. World Congess on Lung Health and 10th ERS Annual Congress, Florence 2000. Eur Respir J 2000; 16 Suppl 31; 295S.

Yıldırım Z, Hasanoğlu HC, Köksal N, Mehmet N, Gökırmak M, Çığlı A. Bronchoconstruction caused by lipid peroxidation due to sulfur dioxide exposure in workers involved apricot sulfurization. European Respiratory Society Annual Congress, Madrid 1999.

Köksal N, Hasanoğlu HC, Yıldırım Z, Gökırmak M, Gültek A, Hacıevliyagil SS. Symptomatic bronchoconstriction by occupational sulfur dioxide exposure in apricot workers. European Respiratory Society Annual Congress, Madrid 1999.

Hasanoğlu HC, YıldırımZ, Köksal N, Gökırmak M, Günal S, Durmaz R. PCR test in bronchial washings to rule out pulmonary tuberculosis. European Respiratory Society Annual Congress, Madrid 1999.

Yıldırım Z, Hasanoğlu HC, Akyol O, Gökırmak M, Köksal N. Serum adenosine deaminase activity in lung cancer and mesothelioma. European Respiratory Society Annual Congress, Geneva 1998.

Hasanoğlu HC, Yıldırım Z, Köksal N, Gökırmak M, Orhan Z, Candan F. The role of atropine in premedication of fiberoptic broncoscopy. European Respiratory Society Annual Congress, Geneva 1998.

Yılmaz Turay U, Yıldırım Z, Türköz Y, Biber Ç, Erdoğan Y, Keyf İ, Uğurman F, Harputluoğlu M. Use of the pleural fluid C-reactive protein in diagnosis of pleural effusion. European Respiratory Society Annual Congress, Geneva 1998.

Hasanoğlu HC, Yıldırım Z, Köksal N, Orhan Z, Günal S, Durmaz R. Clinical utility of bronchial lavage PCR eavaluation in diagnosis of Mycobacterium tuberculosis American College of Chest Physicians New Orleans, Luisianna 1997.

Yıldırım Z, Uçar G, Erdoğan Y, Hasanoğlu HC, Köksal N, Bilen S. Serum angiotensin converting enzyme in asthma. European Respiratory Society Annual Congress, Berlin 1997.